Name | L-741,742 hydrochloride |
---|---|
Supplier | Tocris Bioscience |
Catalog | 1145 |
Prices | $139.00, $579.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 874882-93-6 |
Chemical Name | 5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazolehydrochloride |
Formula | C23H25N2ClO.HCl |
Molecular Weight | 417.38 |
Purity | >98 % |
Description | A potent and highly selective D 4 dopamine receptor antagonist, with K i values of > 1700, 770 and 3.5 nM at cloned human D 2 , D 3 and D 4 receptors. |
Supplier Page | Shop |
Rowley M, Broughton HB, Collins I, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Leeson PD. J Med Chem. 1996 May 10;39(10):1943-5.
Rowley M, Collins I, Broughton HB, Davey WB, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Ball R, Leeson PD. J Med Chem. 1997 Jul 18;40(15):2374-85.