L-798,106

Name	L-798,106
Supplier	Tocris Bioscience
Catalog	2433
Prices	$199.00, $825.00
Sizes	10 mg, 50 mg
Function Type	Antagonist
Cas Number	244101-02-8
Chemical Name	N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide
Formula	C27H22BrNO4S
Molecular Weight	536.44
Purity	>99 %
Description	Potent and highly selective prostanoid EP 3 receptor antagonist (K i values are 0.3, 916, > 5000 and > 5000 nM at EP 3 , EP 4 , EP 1 and EP 2 respectively). Attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo .
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Product References

Differential effects of kinase cascade inhibitors on neoplastic and - Differential effects of kinase cascade inhibitors on neoplastic and

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Small-molecule inhibitors of signal transduction pathways in leukemia - Small-molecule inhibitors of signal transduction pathways in leukemia

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Distinct requirement for an intact dimer interface in wild-type, V600E and - Distinct requirement for an intact dimer interface in wild-type, V600E and

Roring M, Herr R, Fiala GJ, Heilmann K, Braun S, Eisenhardt AE, Halbach S, Capper D, von Deimling A, Schamel WW, Saunders DN, Brummer T. EMBO J. 2012 May 30;31(11):2629-47.