| Name | Latrunculin A |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4757 |
| Prices | $175.00 |
| Sizes | 100 µg |
| Function Type | Inhibitor |
| Cas Number | 76343-93-6 |
| Chemical Name | 4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone |
| Formula | C22H31NO5S |
| Molecular Weight | 421.55 |
| Description | Reversible inhibitor of actin assembly; blocks actin adenine nucleotide exchange. Complexes with actin in vitro and interacts with actin monomers only, unlike cytochalasins. Prevents actin repolymerization into filaments and disrupts the actin cytoskeleton. |
| Supplier Page | Shop |
Morton WM, Ayscough KR, McLaughlin PJ. Nat Cell Biol. 2000 Jun;2(6):376-8.
Yarmola EG, Somasundaram T, Boring TA, Spector I, Bubb MR. J Biol Chem. 2000 Sep 8;275(36):28120-7.