| Name | LCB 03-0110 dihydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4294 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Chemical Name | 3-[[2-[3-(4-Morpholinylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenoldihydrochloride |
| Formula | C24H23N3O2S.2HCl |
| Molecular Weight | 490.45 |
| Purity | >98 % |
| Description | Potent c-Src kinase inhibitor (IC 50 = 1.3 nM). Also potent inhibitor of discoidin domain receptor 2 (DDR2) family tyrosine kinases, BTK and Syk. Suppresses LPS-induced activation of macrophages and TGF- β 1- induced activation of fibroblasts in vitro . Also inhibits activation of macrophages and fibroblasts and suppresses scar formation in a wound healing model. |
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