Name | LDN 212320 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 4828 |
Prices | $129.00, $535.00 |
Sizes | 10 mg, 50 mg |
Cas Number | 894002-50-7 |
Chemical Name | 3-[[(2-Methylphenyl)methyl]thio]-6-(2-pyridinyl)-pyridazine |
Formula | C17H15N3S |
Molecular Weight | 293.39 |
Purity | >98 % |
Description | Increases expression of glutamate transporter EAAT2 in PA-EAAT2 cells. Displays neuroprotective activity in vivo. Shown to improve learning and memory, restore synaptic integrity and reduce amyloid plaque burden in APPSw/Ind mice. |
Supplier Page | Shop |
Xing X, Chang LC, Kong Q, Colton CK, Lai L, Glicksman MA, Lin CL, Cuny GD. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5774-7.
Lin CL, Kong Q, Cuny GD, Glicksman MA. Future Med Chem. 2012 Sep;4(13):1689-700.