Lei-Dab 7

• Supplier: Tocris Bioscience
• Catalog: 1575
• Prices: $309.00
• Sizes: 100 µg
• Function Type: Blocker
• Cas Number: 1061556-49-7
• Formula: C141H236N46O39S6
• Molecular Weight: 3392.06
• Description: High affinity, selective K Ca 2.2 (SK2) channel blocker (K d = 3.8 nM). Exhibits >200-fold selectivity for K Ca 2.2 over K Ca 2.1, K Ca 2.3, K Ca 3.1, IK, K v and K ir 2.1. Increases theta-burst responses and increases LTP in rat hippocampal slices in vitro . Convulsive in vivo .

Product References

Design and characterization of a highly selective peptide inhibitor of the small - Design and characterization of a highly selective peptide inhibitor of the small

Shakkottai VG, Regaya I, Wulff H, Fajloun Z, Tomita H, Fathallah M, Cahalan MD, Gargus JJ, Sabatier JM, Chandy KG. J Biol Chem. 2001 Nov 16;276(46):43145-51. Epub 2001 Aug 29.

A novel mechanism for the facilitation of theta-induced long-term potentiation by - A novel mechanism for the facilitation of theta-induced long-term potentiation by

Kramar EA, Lin B, Lin CY, Arai AC, Gall CM, Lynch G. J Neurosci. 2004 Jun 2;24(22):5151-61.