Leukotriene B 4

Name Leukotriene B 4
Supplier Tocris Bioscience
Catalog 4921
Prices $345.00
Sizes 50 µg
Cas Number 71160-24-2
Chemical Name (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoicacid
Formula C20H32O4
Molecular Weight 336.47
Description Potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT 1 and BLT 2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.
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Product References

Leukotriene B4: an inflammatory mediator in vivo. - Leukotriene B4: an inflammatory mediator in vivo.

Bray MA, Ford-Hutchinson AW, Smith MJ. Prostaglandins. 1981 Aug;22(2):213-22.

Leukotriene B4 in inflammation. - Leukotriene B4 in inflammation.

Ford-Hutchinson AW. Crit Rev Immunol. 1990;10(1):1-12.

Leukotriene B4: metabolism and signal transduction. - Leukotriene B4: metabolism and signal transduction.

Yokomizo T, Izumi T, Shimizu T. Arch Biochem Biophys. 2001 Jan 15;385(2):231-41.