Licarbazepine

Name Licarbazepine
Supplier Tocris Bioscience
Catalog 2705
Prices $109.00, $459.00
Sizes 10 mg, 50 mg
Cas Number 29331-92-8
Chemical Name 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide
Formula C15H14N2O2
Molecular Weight 254.28
Purity >99 %
Description Active metabolite of oxcarbazepine (Cat. No. 3864). Produces dose-dependent inhibition of glutamatergic excitatory postsynaptic potentials (EPSPs). Displays anticonvulsant activity; exhibits minor potentiation of GABA A receptor currents.
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Product References

Action of GP 47779, the active metabolite of oxcarbazepine, on the - Action of GP 47779, the active metabolite of oxcarbazepine, on the

Calabresi P, De Murtas M, Stefani A, Pisani A, Sancesario G, Mercuri NB, Bernardi G. Epilepsia. 1995 Oct;36(10):990-6.

Anticonvulsant and sodium channel-blocking properties of novel - Anticonvulsant and sodium channel-blocking properties of novel

Benes J, Parada A, Figueiredo AA, Alves PC, Freitas AP, Learmonth DA, Cunha RA, Garrett J, Soares-da-Silva P. J Med Chem. 1999 Jul 15;42(14):2582-7.

Oxcarbazepine, not its active metabolite, potentiates GABAA activation and - Oxcarbazepine, not its active metabolite, potentiates GABAA activation and

Zheng T, Clarke AL, Morris MJ, Reid CA, Petrou S, O'Brien TJ. Epilepsia. 2009 Jan;50(1):83-7.