Lin28 1632

• Supplier: Tocris Bioscience
• Catalog: 4745
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 108825-65-6
• Chemical Name: N-Methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide
• Formula: C15H15N5O
• Molecular Weight: 281.31
• Purity: >98 %
• Description: RNA binding protein Lin28 inhibitor (IC 50 = 8 μ M). Blocks binding of Lin28 to let-7 pre-micro RNA. Inhibits stemness and induces differentiation of murine ESCs. Inhibits growth of tumor cell lines and tumor-sphere formation in vitro . Also bromodomain inhibitor.

Product References

Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone - Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone

Brickner SJ, Hutchinson DK, Barbachyn MR, Manninen PR, Ulanowicz DA, Garmon SA, Grega KC, Hendges SK, Toops DS, Ford CW, Zurenko GE. J Med Chem. 1996 Feb 2;39(3):673-9.

In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial - In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial

Ford CW, Hamel JC, Wilson DM, Moerman JK, Stapert D, Yancey RJ Jr, Hutchinson DK, Barbachyn MR, Brickner SJ. Antimicrob Agents Chemother. 1996 Jun;40(6):1508-13.

Linezolid (ZYVOX), the first member of a completely new class of antibacterial - Linezolid (ZYVOX), the first member of a completely new class of antibacterial

Brickner SJ, Barbachyn MR, Hutchinson DK, Manninen PR. J Med Chem. 2008 Apr 10;51(7):1981-90.