LL 37

• Supplier: Tocris Bioscience
• Catalog: 1916
• Prices: $265.00
• Sizes: 1 mg
• Cas Number: 154947-66-7
• Formula: C205H340N60O53
• Molecular Weight: 4493.32
• Description: Antimicrobial peptide derivative of human cathelicidin. Induces FPRL1-mediated chemotaxis of human neutrophils, monocytes and T cells in vitro . Promotes wound healing following skin-targeted electroporation of a plasmid encoding hCAP-18/LL-37 in mice. Also triggers apoptosis in colon cancer cells. Cell permeable.

Product References

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes - LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes

De Yang, Chen Q, Schmidt AP, Anderson GM, Wang JM, Wooters J, Oppenheim JJ, Chertov O. J Exp Med. 2000 Oct 2;192(7):1069-74.

Host immune defense peptide LL-37 activates caspase-independent apoptosis and - Host immune defense peptide LL-37 activates caspase-independent apoptosis and

Ren SX, Cheng AS, To KF, Tong JH, Li MS, Shen J, Wong CC, Zhang L, Chan RL, Wang XJ, Ng SS, Chiu LC, Marquez VE, Gallo RL, Chan FK, Yu J, Sung JJ, Wu WK, Cho CH. Cancer Res. 2012 Dec 15;72(24):6512-23.

Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide - Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide

Steinstraesser L, Lam MC, Jacobsen F, Porporato PE, Chereddy KK, Becerikli M, Stricker I, Hancock RE, Lehnhardt M, Sonveaux P, Preat V, Vandermeulen G. Mol Ther. 2014 Apr;22(4):734-42.