| Name | LMK 235 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5046 |
| Prices | $155.00, $645.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1418033-25-6 |
| Chemical Name | N-[[6-(Hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethylbenzamide |
| Formula | C15H22N2O4 |
| Molecular Weight | 294.35 |
| Purity | >98 % |
| Description | Selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor (IC 50 values are 4.22, 11.9, 55.7, 320, 852, 881, and 1278 nM for HDAC 5, 4, 6, 1, 11, 2, and 8, respectively). Demonstrates activity against chemoresistant cancer cell lines in an MTT assay for cytotoxicity using human ovarian cancer cell lines A2780 and cisplatin resistant A2780CisR (IC 50 = 0.49 and 0.32 μ M respectively). |
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