Lofepramine

• Supplier: Tocris Bioscience
• Catalog: 2314
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 23047-25-8
• Chemical Name: 1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz(Z)[b,f]azepin-5-yl)propyl]methylamino]ethanone
• Formula: C26H27N2OCl
• Molecular Weight: 418.97
• Purity: >99 %
• Description: Serotonin and noradrenalin re-uptake inhibitor (SNRI) that is metabolized to desipramine. Produces inhibition of liver tryptophan pyrollase activity in vitro and displays antidepressant properties in vivo .

Product References

A comparison of the pharmacological properties of the novel tricyclic - A comparison of the pharmacological properties of the novel tricyclic

Leonard BE. Int Clin Psychopharmacol. 1987 Oct;2(4):281-97.

The effects of lofepramine and desmethylimipramine on tryptophan metabolism and - The effects of lofepramine and desmethylimipramine on tryptophan metabolism and

Badawy AA, Morgan CJ, Dacey A, Stoppard T. Biochem Pharmacol. 1991 Jul 25;42(4):921-9.

An investigation of the antidepressant properties of lofepramine and its - An investigation of the antidepressant properties of lofepramine and its

Kelly JP, Leonard BE. Eur Neuropsychopharmacol. 1999 Jan;9(1-2):101-5.