Loratidine

• Supplier: Tocris Bioscience
• Catalog: 0840
• Prices: $109.00, $459.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 79794-75-5
• Chemical Name: 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylicacidethylester
• Formula: C22H23ClN2O2
• Molecular Weight: 382.88
• Purity: >99 %
• Description: Peripheral histamine H 1 receptor antagonist (K i = 35 nM); devoid of central effects. Orally active antiallergic agent.

Product References

Evaluation of the CNS properties of SCH 29851, a potential non-sedating - Evaluation of the CNS properties of SCH 29851, a potential non-sedating

Barnett A, Iorio LC, Kreutner W, Tozzi S, Ahn HS, Gulbenkian A. Agents Actions. 1984 Jun;14(5-6):590-7.

Selective displacement of [3H]mepyramine from peripheral vs. central nervous - Selective displacement of [3H]mepyramine from peripheral vs. central nervous

Ahn HS, Barnett A. Eur J Pharmacol. 1986 Aug 7;127(1-2):153-5.

Antiallergic activity of loratadine, a non-sedating antihistamine. - Antiallergic activity of loratadine, a non-sedating antihistamine.

Kreutner W, Chapman RW, Gulbenkian A, Siegel MI. Allergy. 1987 Jan;42(1):57-63.