Name | Losartan potassium |
---|---|
Supplier | Tocris Bioscience |
Catalog | 1295 |
Prices | $105.00 |
Sizes | 50 mg |
Function Type | Antagonist |
Cas Number | 124750-99-8 |
Chemical Name | 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanolpotassiumsalt |
Formula | C22H22ClKN6O |
Molecular Weight | 461 |
Purity | >99 % |
Description | Selective non-peptide angiotensin AT 1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA 2 = 8.27). Orally active antihypertensive agent. |
Supplier Page | Shop |
Wong PC, Hart SD, Zaspel AM, Chiu AT, Ardecky RJ, Smith RD, Timmermans PB. J Pharmacol Exp Ther. 1990 Nov;255(2):584-92.
Wong PC, Price WA, Chiu AT, Duncia JV, Carini DJ, Wexler RR, Johnson AL, Timmermans PB. J Pharmacol Exp Ther. 1990 Feb;252(2):719-25.
Rhaleb NE, Rouissi N, Nantel F, D'Orleans-Juste P, Regoli D. Hypertension. 1991 Apr;17(4):480-4.