Name | LTURM 34 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 5275 |
Prices | $189.00, $795.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 1879887-96-3 |
Chemical Name | 8-(4-Dibenzothienyll)-2-(4-morpholinyl)-4H-1,3-benzoxazin-4-one |
Formula | C24H18N2O3S |
Molecular Weight | 414.48 |
Purity | >98 % |
Description | Potent DNA-PK inhibitor (IC 50 = 34 nM). Exhibits 170-fold selectivity for DNA-PK over PI3-K. Attenuates proliferation of a wide range of tumor cell lines in vitro . |
Supplier Page | Shop |
Sams AG, Mikkelsen GK, Larsen M, Langgard M, Howells ME, Schroder TJ, Brennum LT, Torup L, Jorgensen EB, Bundgaard C, Kreilgard M, Bang-Andersen B. J Med Chem. 2011 Feb 10;54(3):751-64. Epub 2011 Jan 6.
Collins LE, Sager TN, Sams AG, Pennarola A, Port RG, Shahriari M, Salamone JD. Pharmacol Biochem Behav. 2012 Jan;100(3):498-505.