| Name | LU AA33810 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4783 |
| Prices | $159.00, $665.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 304008-29-5 |
| Chemical Name | N-[[trans-4-[(4,5-Dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]methanesulfonamide |
| Formula | C19H25N3O2S3 |
| Molecular Weight | 423.62 |
| Purity | >98 % |
| Description | Potent neuropeptide Y (NPY) Y 5 receptor antagonist (K i = 1.5 nM in vitro ). Displays ≥ 3300-fold affinity for Y 5 over Y 1 , Y 2 and Y 4 receptors. Also binds human 5-HT 2B and 5-HT 1A receptors (K i values are 247 and 478 nM respectively). Exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity. |
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