Luteolin

• Supplier: Tocris Bioscience
• Catalog: 4881
• Prices: $89.00, $355.00
• Sizes: 10 mg, 50 mg
• Function Type: Antioxidant
• Cas Number: 491-70-3
• Chemical Name: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
• Formula: C15H10O6
• Molecular Weight: 286.24
• Purity: >98 %
• Description: Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF- α , IL-6 and inducible nitric oxide production and blocks NF- κ B and AP-1 activation. Also inhibits TNF- α -induced COX-2 expression. Antiproliferative and chemopreventative; inhibits proliferation of Lewis lung carcinoma cells in vivo .

Product References

Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB - Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB

Chen CY, Peng WH, Tsai KD, Hsu SL. Life Sci. 2007 Nov 30;81(23-24):1602-14. Epub 2007 Oct 5.

A critical role of luteolin-induced reactive oxygen species in blockage of tumor - A critical role of luteolin-induced reactive oxygen species in blockage of tumor

Ju W, Wang X, Shi H, Chen W, Belinsky SA, Lin Y. Mol Pharmacol. 2007 May;71(5):1381-8. Epub 2007 Feb 12.