| Name | LY 2389575 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3397 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Modulator |
| Cas Number | 885104-09-6 |
| Chemical Name | (3S)-N-(2,4-Dichlorobenzyl)-1-(5-bromopyrimidin-2-yl)pyrrolidinyl-3-aminehydrochloride |
| Formula | C15H15BrCl2N4.HCl |
| Molecular Weight | 438.58 |
| Purity | >98 % |
| Description | Selective negative allosteric modulator of mGlu 3 (IC 50 = 190 nM). Exhibits > 65-fold selectivity for mGlu 3 over other mGlu receptors. Abolishes the neuroprotective action of LY 379268 against amyloid β toxicity in mixed cortical neuronal and astrocyte cell cultures. |
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