LY 266097 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2208
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 172895-39-5
• Chemical Name: 1-[(2-Chloro-3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-1H-pyrido[3,4-b]indolehydrochloride
• Formula: C21H23ClN2O2.HCl
• Molecular Weight: 407.33
• Purity: >99 %
• Description: Selective 5-HT 2B receptor antagonist (pK i = 9.3). More than 100-fold selective over 5-HT 2A and 5-HT 2C . Attenuates amphetamine-induced locomotion in the rat.

Product References

Potent, selective tetrahydro-beta-carboline antagonists of the serotonin 2B - Potent, selective tetrahydro-beta-carboline antagonists of the serotonin 2B

Audia JE, Evrard DA, Murdoch GR, Droste JJ, Nissen JS, Schenck KW, Fludzinski P, Lucaites VL, Nelson DL, Cohen ML. J Med Chem. 1996 Jul 5;39(14):2773-80.

The central serotonin 2B receptor: a new pharmacological target to modulate the - The central serotonin 2B receptor: a new pharmacological target to modulate the

Auclair AL, Cathala A, Sarrazin F, Depoortere R, Piazza PV, Newman-Tancredi A, Spampinato U. J Neurochem. 2010 Sep 1;114(5):1323-32.