LY 272015 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4081
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 172895-15-7
• Chemical Name: 1-[(3,4-Dimethoxyphenyl)methy]-2,3,4,9-tetrahydro-6-methyl-1H-pyrido[3,4-b]indolehydrochloride
• Formula: C21H24N2O2.HCl
• Molecular Weight: 372.89
• Purity: >99 %
• Description: High affinity 5-HT 2B receptor antagonist that displays selectivity over 5-HT 2A and 5-HT 2C receptors (K i values are 0.75, 21.63 and 28.7 nM for 5-HT 2B , 5-HT 2C and 5-HT 2A receptors respectively). Orally active.

Product References

In vivo modulation of vagal-identified dorsal medullary neurones by activation of - In vivo modulation of vagal-identified dorsal medullary neurones by activation of

Sevoz-Couche C, Spyer KM, Jordan D. Br J Pharmacol. 2000 Dec;131(7):1445-53.

Expression and function of serotonin 2A and 2B receptors in the mammalian - Expression and function of serotonin 2A and 2B receptors in the mammalian

Niebert M, Vogelgesang S, Koch UR, Bischoff AM, Kron M, Bock N, Manzke T. PLoS One. 2011;6(7):e21395.