LY 78335

• Supplier: Tocris Bioscience
• Catalog: 3283
• Prices: $105.00, $445.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 39959-66-5
• Chemical Name: 2,3-Dichloro-α-methylbenzylaminehydrochloride
• Formula: C8H9Cl2N.HCl
• Molecular Weight: 226.53
• Purity: >99 %
• Description: High affinity inhibitor of phenylethanolamine- N -methyltransferase (PNMT) (K i = 0.09 μ M in vitro ). Suppresses the release of growth hormone in an in vivo rat model.

Product References

Inhibition of phenylethanolamine N-methyltransferase by benzylamines. 2. In vitro - Inhibition of phenylethanolamine N-methyltransferase by benzylamines. 2. In vitro

Fuller RW, Roush BW, Snoddy HD, Molloy BB. J Med Chem. 1973 Feb;16(2):106-9.

Regulation of episodic growth hormone secretion by the central epinephrine - Regulation of episodic growth hormone secretion by the central epinephrine

Terry LC, Crowley WR, Johnson MD. J Clin Invest. 1982 Jan;69(1):104-12.

Synthesis and evaluation of 3-substituted analogues of - Synthesis and evaluation of 3-substituted analogues of

Grunewald GL, Sall DJ, Monn JA. J Med Chem. 1988 Apr;31(4):824-30.