Lyn peptide inhibitor

Name Lyn peptide inhibitor
Supplier Tocris Bioscience
Catalog 4060
Prices $319.00
Sizes 1 mg
Function Type Inhibitor
Cas Number 222018-18-0
Formula C115H184N30O24
Molecular Weight 2370.91
Description Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to β c subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinophil differentiation and survival in vitro . Inhibits airway eosinophilic inflammation in mouse model of asthma.
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Product References

The mapping of the Lyn kinase binding site of the common beta subunit of - The mapping of the Lyn kinase binding site of the common beta subunit of

Adachi T, Pazdrak K, Stafford S, Alam R. J Immunol. 1999 Feb 1;162(3):1496-501.

A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, - A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation,

Adachi T, Stafford S, Sur S, Alam R. J Immunol. 1999 Jul 15;163(2):939-46.