M 344

• Supplier: Tocris Bioscience
• Catalog: 4917
• Prices: $65.00, $139.00, $585.00
• Sizes: 1 mg, 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 251456-60-7
• Chemical Name: 4-(Diethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
• Formula: C16H25N3O3
• Molecular Weight: 307.39
• Purity: >98 %
• Description: Histone deacetylase inhibitor (IC 50 = 100 nM). Induces terminal cell differentiation and causes an increase in hyperacetylated histone H4. Antiproliferative agent; suppresses the growth of human endometrial and ovarian cancer cells by inducing cell cycle arrest and apoptosis.

Product References

Amide analogues of trichostatin A as inhibitors of histone deacetylase and - Amide analogues of trichostatin A as inhibitors of histone deacetylase and

Jung M, Brosch G, Kolle D, Scherf H, Gerhauser C, Loidl P. J Med Chem. 1999 Nov 4;42(22):4669-79.

The benzamide M344, a novel histone deacetylase inhibitor, significantly - The benzamide M344, a novel histone deacetylase inhibitor, significantly

Riessland M, Brichta L, Hahnen E, Wirth B. Hum Genet. 2006 Aug;120(1):101-10. Epub 2006 May 25.

M344 is a novel synthesized histone deacetylase inhibitor that induces growth - M344 is a novel synthesized histone deacetylase inhibitor that induces growth

Takai N, Ueda T, Nishida M, Nasu K, Narahara H. Gynecol Oncol. 2006 Apr;101(1):108-13. Epub 2005 Nov 2.