M8 B hydrochloride

Name M8 B hydrochloride
Supplier Tocris Bioscience
Catalog 2697
Prices $165.00, $675.00
Sizes 10 mg, 50 mg
Function Type Blocker
Cas Number 883976-12-3
Chemical Name N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamidehydrochloride
Formula C22H24N2O3S.HCl
Molecular Weight 432.96
Purity >99 %
Description Potent and selective TRPM8 channel blocker. Blocks cold- and icilin -induced TRPM8 activation in vitro (IC 50 values are 7.8 and 26.9 nM respectively). Exhibits no effect at other TRP channels (IC 50 > 20 μ M). Reduces body temperature in vivo .
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