McN-A 343

• Supplier: Tocris Bioscience
• Catalog: 2148
• Prices: $59.00, $225.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 55-45-8
• Chemical Name: 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminiumchloride
• Formula: C14H18Cl2N2O2
• Molecular Weight: 317.21
• Purity: >99 %
• Description: Selective muscarinic M 1 receptor agonist. Selectivity for M 1 over other muscarinic receptor types appears to arise from a high efficacy at M 1 receptors.

Product References

Functional determination of McN-A-343 affinity for M1 muscarinic receptors. - Functional determination of McN-A-343 affinity for M1 muscarinic receptors.

Micheletti R, Schiavone A. J Pharmacol Exp Ther. 1990 Apr;253(1):310-4.

Muscarinic receptor subtypes and smooth muscle function. - Muscarinic receptor subtypes and smooth muscle function.

Eglen RM, Hegde SS, Watson N. Pharmacol Rev. 1996 Dec;48(4):531-65.

Inhibition of field stimulation-induced contractions of rabbit vas deferens by - Inhibition of field stimulation-induced contractions of rabbit vas deferens by

Davies RH, Scholes HE, Virdi S, Broadley KJ. J Pharm Pharmacol. 2001 Apr;53(4):487-96.