( S )-MCPG

• Supplier: Tocris Bioscience
• Catalog: 0336
• Prices: $255.00, $1,045.00
• Sizes: 10 mg, 50 mg
• Cas Number: 150145-89-4
• Chemical Name: (S)-α-Methyl-4-carboxyphenylglycine
• Formula: C10H11NO4
• Molecular Weight: 209.2
• Purity: >99 %
• Description: Active isomer of ( RS )-MCPG (Cat. No. 0336). Non-selective group I/group II metabotropic glutamate receptor antagonist. Also available as part of the Group I mGlu Receptor Tocriset™ , Group II mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ .

Product References

Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of - Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of

Jane DE, Jones PL, Pook PC, Salt TE, Sunter DC, Watkins JC. Neuropharmacology. 1993 Jul;32(7):725-7.

Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. - Phenylglycine derivatives as antagonists of metabotropic glutamate receptors.

Watkins J, Collingridge G. Trends Pharmacol Sci. 1994 Sep;15(9):333-42.

Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and - Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and

Bordi F, Marcon C, Chiamulera C, Reggiani A. Neuropharmacology. 1996;35(11):1557-65.

Structure-activity relationships of new agonists and antagonists of different - Structure-activity relationships of new agonists and antagonists of different

Sekiyama N, Hayashi Y, Nakanishi S, Jane DE, Tse HW, Birse EF, Watkins JC. Br J Pharmacol. 1996 Apr;117(7):1493-503.