MDL 100907

• Supplier: Tocris Bioscience
• Catalog: 3982
• Prices: $249.00, $1,025.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 139290-65-6
• Chemical Name: (R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol
• Formula: C22H28FNO3
• Molecular Weight: 373.46
• Purity: >98 %
• Description: Potent and selective 5-HT 2A receptor antagonist (K i = 0.36 nM). Exhibits > 80-fold selectivity for 5-HT 2A over other serotonergic receptor subtypes. Antipsychotic agent in vivo .

Product References

Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative - Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative

Sorensen SM, Kehne JH, Fadayel GM, Humphreys TM, Ketteler HJ, Sullivan CK, Taylor VL, Schmidt CJ. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91.

Preclinical characterization of the potential of the putative atypical - Preclinical characterization of the potential of the putative atypical

Kehne JH, Baron BM, Carr AA, Chaney SF, Elands J, Feldman DJ, Frank RA, van Giersbergen PL, McCloskey TC, Johnson MP, McCarty DR, Poirot M, Senyah Y, Siegel BW, Widmaier C. J Pharmacol Exp Ther. 1996 May;277(2):968-81.

The 5-hydroxytryptamine2A receptor antagonist - The 5-hydroxytryptamine2A receptor antagonist

Ardayfio PA, Benvenga MJ, Chaney SF, Love PL, Catlow J, Swanson SP, Marek GJ. J Pharmacol Exp Ther. 2008 Dec;327(3):891-7.