MDL 12330A hydrochloride

Name MDL 12330A hydrochloride
Supplier Tocris Bioscience
Catalog 0870
Prices $109.00, $459.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 40297-09-4
Chemical Name (±)-N-[(1R*,2R*)-2-Phenylcyclopentyl]-azacyclotridec-1-en-2-aminehydrochloride
Formula C23H36N2.HCl
Molecular Weight 377.01
Purity >98 %
Description Inhibitor of adenylyl cyclase. Also inhibits cAMP and cGMP phosphodiesterases, and blocks slow extracellular and store-operated Ca 2+ entry into cells.
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Product References

RMI 12330 A, an inhibitor of adenylate cyclase in rat liver. - RMI 12330 A, an inhibitor of adenylate cyclase in rat liver.

Guellaen G, Mahu JL, Mavier P, Berthelot P, Hanoune J. Biochim Biophys Acta. 1977 Oct 13;484(2):465-75.

RMI 12330A, an inhibitor of cyclic nucleotide phosphodiesterases and adenylate - RMI 12330A, an inhibitor of cyclic nucleotide phosphodiesterases and adenylate

Hunt NH, Evans T. Biochim Biophys Acta. 1980 Jun 13;613(2):499-506.

Ca2+ entry mediated by store depletion, S-nitrosylation, and TRP3 channels. - Ca2+ entry mediated by store depletion, S-nitrosylation, and TRP3 channels.

van Rossum DB, Patterson RL, Ma HT, Gill DL. J Biol Chem. 2000 Sep 15;275(37):28562-8.