MEDICA 16

• Supplier: Tocris Bioscience
• Catalog: 5160
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 87272-20-6
• Chemical Name: 3,3,14,14-Tetramethylhexadecanedioicacid
• Formula: C20H38O4
• Molecular Weight: 342.51
• Description: Free fatty acid 1 (FFA1/GPR40) receptor agonist; exhibits selectivity for FFA1 (GPR40) over GPR120. Also inhibits ATP citrate lyase; reduces intracellular triacylglycerol levels in muscle, inhibits lipogenesis and increases insulin sensitivity in rodents in vivo .

Product References

MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma - MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma

Atkinson LL, Kelly SE, Russell JC, Bar-Tana J, Lopaschuk GD. Diabetes. 2002 May;51(5):1548-55.

Novel selective ligands for free fatty acid receptors GPR120 and GPR40. - Novel selective ligands for free fatty acid receptors GPR120 and GPR40.

Hara T, Hirasawa A, Sun Q, Sadakane K, Itsubo C, Iga T, Adachi T, Koshimizu TA, Hashimoto T, Asakawa Y, Tsujimoto G. Naunyn Schmiedebergs Arch Pharmacol. 2009 Sep;380(3):247-55. doi: