Mesopram

• Supplier: Tocris Bioscience
• Catalog: 4103
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 189940-24-7
• Chemical Name: (R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone
• Formula: C14H19NO4
• Molecular Weight: 265.31
• Purity: >98 %
• Description: Orally active phosphodiesterase (PDE) 4 inhibitor. Inhibits Th1 cell proliferation and decreases production of IFN- γ , TNF- α , IL-10 and iNOS in vitro . Triggers ovulation and exhibits efficacy against experimental autoimmune encephalomyelitis and murine colitis in vivo .

Product References

The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental - The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental

Dinter H, Tse J, Halks-Miller M, Asarnow D, Onuffer J, Faulds D, Mitrovic B, Kirsch G, Laurent H, Esperling P, Seidelmann D, Ottow E, Schneider H, Tuohy VK, Wachtel H, Perez HD. J Neuroimmunol. 2000 Aug 1;108(1-2):136-46.

The specific type-4 phosphodiesterase inhibitor mesopram alleviates experimental - The specific type-4 phosphodiesterase inhibitor mesopram alleviates experimental

Loher F, Schmall K, Freytag P, Landauer N, Hallwachs R, Bauer C, Siegmund B, Rieder F, Lehr HA, Dauer M, Kapp JF, Endres S, Eigler A. J Pharmacol Exp Ther. 2003 May;305(2):549-56. Epub 2003 Feb 11.

Pharmacological inhibition of phosphodiesterase 4 triggers ovulation in - Pharmacological inhibition of phosphodiesterase 4 triggers ovulation in

McKenna SD, Pietropaolo M, Tos EG, Clark A, Fischer D, Kagan D, Bao B, Chedrese PJ, Palmer S. Endocrinology. 2005 Jan;146(1):208-14. Epub 2004 Sep 24.