Mesulergine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 3053
• Prices: $185.00, $755.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 72786-12-0
• Chemical Name: N'-[(8-α1,6-dimethylergolin-8-yl]-N,N-dimethylsulfamidehydrochloride
• Formula: C18H26N4O2S.HCl
• Molecular Weight: 398.95
• Purity: >99 %
• Description: 5-HT 2A and 2C receptor antagonist (pA 2 values are 9.1 for each receptor) and D 2 -like dopamine receptor partial agonist (K i = 8 nM). Displays antiprolactin and antiparkinsonian effects in vivo .

Product References

Mesulergine and its 1,20-N,N-bidemethylated metabolite interact directly with D1- - Mesulergine and its 1,20-N,N-bidemethylated metabolite interact directly with D1-

Markstein R. Eur J Pharmacol. 1983 Nov 11;95(1-2):101-7.

Dopamine agonistic potency of two novel prolactin release-inhibiting ergolines. - Dopamine agonistic potency of two novel prolactin release-inhibiting ergolines.

Marko M. Eur J Pharmacol. 1984 Jun 1;101(3-4):263-6.

International Union of Pharmacology classification of receptors for - International Union of Pharmacology classification of receptors for

Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP. Pharmacol Rev. 1994 Jun;46(2):157-203.