3-Methyladenine

Name 3-Methyladenine
Supplier Tocris Bioscience
Catalog 0577
Prices $105.00
Sizes 50 mg
Function Type Inhibitor
Cas Number 5142-23-4
Chemical Name 3-Methyl-3H-purin-6-amine
Formula C6H7N5
Molecular Weight 149.15
Purity >99 %
Description Inhibitor of class III phosphatidylinositol 3-kinase (PI 3-kinase); also inhibits the autophagic sequestration of cell proteins in rat hepatocytes. Blocks apoptosis in cerebellar granule cells (CGCs) following serum and potassium deprivation.
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Product References

The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit - The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit

Blommaart EF, Krause U, Schellens JP, Vreeling-Sindelarova H, Meijer AJ. Eur J Biochem. 1997 Jan 15;243(1-2):240-6.

Role of the autophagic-lysosomal system on low potassium-induced apoptosis in - Role of the autophagic-lysosomal system on low potassium-induced apoptosis in

Canu N, Tufi R, Serafino AL, Amadoro G, Ciotti MT, Calissano P. J Neurochem. 2005 Mar;92(5):1228-42.