Name | 1-Methyl- D -tryptophan |
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Supplier | Tocris Bioscience |
Catalog | 0584 |
Prices | $69.00 |
Sizes | 50 mg |
Function Type | Inhibitor |
Cas Number | 110117-83-4 |
Formula | C12H14N2O2 |
Molecular Weight | 218.25 |
Purity | >97 % |
Description | Indoleamine 2,3-dioxygenase (IDO) inhibitor (IC 50 = 7 μ M); disrupts tryptophan catabolism. Enhances the antitumor and antiviral immunoresponses of CD8+ T-cells in vitro . Reduces tumor volume in mice with xenografts overexpressing IDO. |
Supplier Page | Shop |
Hwang TL, Wu CC, Teng CM. Br J Pharmacol. 1998 Nov;125(6):1158-63.
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