Mexiletine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 1526
• Prices: $75.00
• Sizes: 50 mg
• Function Type: Blocker
• Cas Number: 5370-01-4
• Chemical Name: 1-(2,6-Dimethylphenoxy)-2-propanaminehydrochloride
• Formula: C11H17NO.HCl
• Molecular Weight: 215.72
• Purity: >99 %
• Description: Use-dependent sodium channel blocker (IC 50 values are 75.3 and 23.6 μ M for tonic and use-dependent block respectively). Class Ib antiarrhythmic, neuroprotective and antimyotonic agent.

Product References

Optically active mexiletine analogues as stereoselective blockers of - Optically active mexiletine analogues as stereoselective blockers of

Franchini C, Carocci A, Catalano A, Cavalluzzi MM, Corbo F, Lentini G, Scilimati A, Tortorella P, Camerino DC, De Luca A. J Med Chem. 2003 Nov 20;46(24):5238-48.

Neuroprotective effect of mexiletine in the central nervous system of diabetic - Neuroprotective effect of mexiletine in the central nervous system of diabetic

Ates O, Cayli SR, Altinoz E, Yucel N, Kocak A, Tarim O, Durak A, Turkoz Y, Yologlu S. Mol Cell Biochem. 2006 Jun;286(1-2):125-31. Epub 2006 Mar 16.

Evaluation of the pharmacological activity of the major mexiletine metabolites on - Evaluation of the pharmacological activity of the major mexiletine metabolites on

De Bellis M, De Luca A, Rana F, Cavalluzzi MM, Catalano A, Lentini G, Franchini C, Tortorella V, Conte Camerino D. Br J Pharmacol. 2006 Oct;149(3):300-10. Epub 2006 Aug 21.