Name | MI 192 |
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Supplier | Tocris Bioscience |
Catalog | 5604 |
Prices | $199.00 |
Sizes | 10 mg |
Function Type | Inhibitor |
Cas Number | 1415340-63-4 |
Chemical Name | N-(2-Aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]benzamide |
Formula | C24H21N3O2 |
Molecular Weight | 383.44 |
Purity | >98 % |
Description | Potent and selective HDAC2/3 inhibitor (IC 50 values are 16 and 30 nM, respectively). Exhibits >250-fold selectivity for HDAC2/3 over other HDAC isoforms. Promotes apoptosis of leukemia cell lines in vitro . Also attenuates IL-6 production in rheumatoid arthritis PBMCs in vitro . |
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