Mianserin hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4848
• Prices: $75.00
• Sizes: 50 mg
• Function Type: Antagonist
• Cas Number: 21535-47-7
• Chemical Name: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepinehydrochloride
• Formula: C18H20N2.HCl
• Molecular Weight: 300.83
• Purity: >99 %
• Description: Non-selective 5-HT 2 receptor antagonist (K i values are 0.0080 and 0.0081 μ M for human 5-HT 2A and 5-HT 2C receptors expressed in HEK293 cells respectively). Has moderate affinity for 5-HT 6 . Antidepressant.

Product References

On the mode of action of mianserin. - On the mode of action of mianserin.

Leonard BE. Adv Biochem Psychopharmacol. 1982;31:301-19.

International Union of Pharmacology classification of receptors for - International Union of Pharmacology classification of receptors for

Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP. Pharmacol Rev. 1994 Jun;46(2):157-203.

Design, synthesis, and pharmacological characterization of N- and O-substituted - Design, synthesis, and pharmacological characterization of N- and O-substituted

Jensen AA, Plath N, Pedersen MH, Isberg V, Krall J, Wellendorph P, Stensbol TB, Gloriam DE, Krogsgaard-Larsen P, Frolund B. J Med Chem. 2013 Feb 14;56(3):1211-27.