Miglitol

• Supplier: Tocris Bioscience
• Catalog: 1479
• Prices: $175.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 72432-03-2
• Chemical Name: (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(2-hydroxymethyl)-3,4,5-piperidinetriol
• Formula: C8H17NO5
• Molecular Weight: 207.22
• Purity: >98 %
• Description: Inhibitor of α -glucosidase; antihyperglycemic. Suppresses postprandial hyperglycemia in vivo and reduces plasma glucose concentration in normal rats and in several animal models of diabetes. Shown to inhibit the loss of pancreatic β cells in type 2 diabetic rats. Also inhibits apoptosis and mitochondrial overproduction of reactive oxygen species in endothelial cells in vitro .

Product References

Miglitol, a new alpha-glucosidase inhibitor. - Miglitol, a new alpha-glucosidase inhibitor.

Sels JP, Huijberts MS, Wolffenbuttel BH. Expert Opin Pharmacother. 1999 Nov;1(1):149-56.

Effects of miglitol, an alpha-glucosidase inhibitor, on glycaemic status and - Effects of miglitol, an alpha-glucosidase inhibitor, on glycaemic status and

Goda T, Suruga K, Komori A, Kuranuki S, Mochizuki K, Makita Y, Kumazawa T. Br J Nutr. 2007 Oct;98(4):702-10. Epub 2007 May 31.

Miglitol, an anti-diabetic drug, inhibits oxidative stress-induced apoptosis and - Miglitol, an anti-diabetic drug, inhibits oxidative stress-induced apoptosis and

Aoki C, Suzuki K, Yanagi K, Satoh H, Niitani M, Aso Y. J Pharmacol Sci. 2012;120(2):121-8. Epub 2012 Sep 26.