Milnacipran hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2604
• Prices: $99.00, $419.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 101152-94-7
• Chemical Name: (1R*,2S*)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamidehydrochloride
• Formula: C15H22N2O.HCl
• Molecular Weight: 282.81
• Purity: >99 %
• Description: Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .

Product References

Biochemical profile of midalcipran (F 2207), - Biochemical profile of midalcipran (F 2207),

Moret C, Charveron M, Finberg JP, Couzinier JP, Briley M. Neuropharmacology. 1985 Dec;24(12):1211-9.

Pharmacological effects of milnacipran, a new antidepressant, given repeatedly on - Pharmacological effects of milnacipran, a new antidepressant, given repeatedly on

Maj J, Rogoz Z, Dlaboga D, Dziedzicka-Wasylewska M. J Neural Transm. 2000;107(11):1345-59.

Antiallodynic and antihyperalgesic effect of milnacipran in mice with spinal - Antiallodynic and antihyperalgesic effect of milnacipran in mice with spinal

Suzuki T, Ueta K, Tamagaki S, Mashimo T. Anesth Analg. 2008 Apr;106(4):1309-15, table of contents. doi: