Milrinone

• Supplier: Tocris Bioscience
• Catalog: 3286
• Prices: $175.00, $709.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 78415-72-2
• Chemical Name: 1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile
• Formula: C12H9N3O
• Molecular Weight: 211.22
• Purity: >98 %
• Description: Potent cAMP phosphodiesterase inhibitor (IC 50 = 56 nM for inhibition of PDE III). Has inotropic and vasodilator effects following oral or intravenous administration in vivo . Also available as part of the Phosphodiesterase Inhibitor Tocriset™ .

Product References

Characterization of the cardiotonic effects of milrinone, a new and potent - Characterization of the cardiotonic effects of milrinone, a new and potent

Alousi AA, Stankus GP, Stuart JC, Walton LH. J Cardiovasc Pharmacol. 1983 Sep-Oct;5(5):804-11.

The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in - The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in

Shahid M, van Amsterdam RG, de Boer J, ten Berge RE, Nicholson CD, Zaagsma J. Br J Pharmacol. 1991 Oct;104(2):471-7.

Photoaffinity labelling of cyclic GMP-inhibited phosphodiesterase (PDE III) in - Photoaffinity labelling of cyclic GMP-inhibited phosphodiesterase (PDE III) in

Tang KM, Jang EK, Haslam RJ. Eur J Pharmacol. 1994 Jun 15;268(1):105-14.