Mirtazapine

• Supplier: Tocris Bioscience
• Catalog: 3190
• Prices: $109.00, $459.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 85650-52-8
• Chemical Name: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
• Formula: C17H19N3
• Molecular Weight: 265.36
• Purity: >99 %
• Description: Antidepressant agent; potent 5-HT 2 , 5-HT 3 and histamine H 1 receptor antagonist and moderately potent α 2 -adrenoceptor antagonist (pK i values are 8.05, ~ 8.1, 9.3 and 6.95 respectively). Enhances noradrenalin (NA) release in rat brain via inhibition of α 2 -adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pK i values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo .

Product References

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