MitMAB

• Supplier: Tocris Bioscience
• Catalog: 1489
• Prices: $59.00, $249.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1119-97-7
• Chemical Name: Tetradecyltrimethylammoniumbromide
• Formula: C17H38BrN
• Molecular Weight: 336.39
• Description: Dynamin inhibitor; inhibits the GTPase activity of dynamin I (K i = 940 nM; IC 50 = 3.1 μ M). Targets the dynamin-phospholipid interaction. Inhibits receptor-mediated endocytosis of epidermal growth factor (EGF) in non-neuronal cells; also inhibits synaptic vesicle endocytosis. Displays dynamin I-inhibitory activity similar to OctMAB (Cat. No. 4225).

Product References

Long chain amines and long chain ammonium salts as novel inhibitors of dynamin - Long chain amines and long chain ammonium salts as novel inhibitors of dynamin

Hill TA, Odell LR, Quan A, Abagyan R, Ferguson G, Robinson PJ, McCluskey A. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3275-8.

Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are - Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are

Quan A, McGeachie AB, Keating DJ, van Dam EM, Rusak J, Chau N, Malladi CS, Chen C, McCluskey A, Cousin MA, Robinson PJ. Mol Pharmacol. 2007 Dec;72(6):1425-39. Epub 2007 Aug 16.