| Name | ML 221 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4507 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 877636-42-5 |
| Chemical Name | 5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one |
| Formula | C17H11N3O6S |
| Molecular Weight | 385.35 |
| Purity | >99 % |
| Description | Apelin receptor (APJ) antagonist (IC 50 values are 0.70 and 1.75 μ M in a cAMP assay and β -arrestin assay, respectively). Displays >37-fold selectivity over the closely related angiotensin II type 1 (AT 1 ) receptor. Exhibits no toxicity towards human hepatocytes at concentrations >50 μ M. |
| Supplier Page | Shop |