ML 233

• Supplier: Tocris Bioscience
• Catalog: 4565
• Prices: $159.00, $669.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Chemical Name: (E)-4-Methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one
• Formula: C19H21NO4S
• Molecular Weight: 359.44
• Purity: >98 %
• Description: Non-peptide apelin receptor agonist (EC 50 = 3.7 μ M); exhibits >21-fold selectivity over the closely related angiotensin 1 receptor (EC 50 = >79 μ M).

Product References

Phenotypic high-throughput screening elucidates target pathway in breast cancer - Phenotypic high-throughput screening elucidates target pathway in breast cancer

Carmody LC, Germain AR, VerPlank L, Nag PP, Munoz B, Perez JR, Palmer MA. J Biomol Screen. 2012 Oct;17(9):1204-10. Epub 2012 Aug 30.

Identification of a selective small molecule inhibitor of breast cancer stem - Identification of a selective small molecule inhibitor of breast cancer stem

Germain AR, Carmody LC, Morgan B, Fernandez C, Forbeck E, Lewis TA, Nag PP, Ting A, VerPlank L, Feng Y, Perez JR, Dandapani S, Palmer M, Lander ES, Gupta PB, Schreiber SL, Munoz B. Bioorg Med Chem Lett. 2012 May 15;22(10):3571-4.