| Name | ML 339 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4982 |
| Prices | $125.00, $525.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Chemical Name | N-[(1R,3S,5S)-9-(2-((2-Chlorophenyl)amino)-2-exoethyl)-9-azabicyclo[3.3.1]nonan-3-yl)-3,4,5-trimethoxybenzamide |
| Formula | C26H32ClN3O5 |
| Molecular Weight | 502 |
| Purity | >98 % |
| Description | Potent and selective hCXCR6 antagonist (IC 50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC 50 = 18 μ M). Exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors (IC 50 >79 μ M). |
| Supplier Page | Shop |
Laufer SA, Wagner GK, Kotschenreuther DA, Albrecht W. J Med Chem. 2003 Jul 17;46(15):3230-44.
Kammerer B, Scheible H, Albrecht W, Gleiter CH, Laufer S. Drug Metab Dispos. 2007 Jun;35(6):875-83. Epub 2007 Mar 7.