| Name | ML 347 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4586 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1062368-49-3 |
| Chemical Name | 5-[6-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline |
| Formula | C22H16N4O |
| Molecular Weight | 352.39 |
| Purity | >98 % |
| Description | Potent and selective ALK2 and ALK1 inhibitor (IC 50 values are 32 and 46 nM, respectively); displays >200 fold selectivity over ALK3 and ALK6 and >400 fold selectivity over VEGF2. Exhibits no activity at ALK4, ALK5 or in a panel of related kinases. Inhibits BMP4 signaling in a functional assay (IC 50 = 152 nM). |
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