ML 382

• Supplier: Tocris Bioscience
• Catalog: 5337
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Modulator
• Cas Number: 1646499-97-9
• Chemical Name: 2-[(Cyclopropylsulfonyl)amino]-N-(2-ethoxyphenyl)benzamide
• Formula: C18H20N2O4S
• Molecular Weight: 360.43
• Purity: >98 %
• Description: Selective MrgX1 (SNSR4) positive allosteric modulator (EC 50 = 190 nM). Exhibits selectivity for MrgX1 over MrgX2, MrgC11 and a panel of 68 other GPCRs, ion channels and transporters. Enhances BAM (8-22) potency at MrgX1 by 7-fold.

Product References

Selective inhibition of catalytic activity of smooth muscle myosin light chain - Selective inhibition of catalytic activity of smooth muscle myosin light chain

Saitoh M, Ishikawa T, Matsushima S, Naka M, Hidaka H. J Biol Chem. 1987 Jun 5;262(16):7796-801.

Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and - Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and

Meinders M, Kulu DI, van de Werken HJ, Hoogenboezem M, Janssen H, Brouwer RW, van Ijcken WF, Rijkers EJ, Demmers JA, Kruger I, van den Berg TK, Suske G, Gutierrez L, Philipsen S. Blood. 2015 Mar 19;125(12):1957-67.