MLi-2

• Supplier: Tocris Bioscience
• Catalog: 1885
• Prices: $249.00, $1,049.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1627091-47-7
• Chemical Name: rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole
• Formula: C21H25N5O2
• Molecular Weight: 379.46
• Purity: >98 %
• Description: Potent and selective LRRK2 inhibitor (IC 50 = 0.76-3.4 nM depending on assay). Exhibits >295-fold selectivity for over 300 kinases and a diverse panel of receptors and ion channels. Centrally bioavailable and active in vivo .

Product References

The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that - The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that

Ochman AR, Lipinski CA, Handler JA, Reaume AG, Saporito MS. J Pharmacol Exp Ther. 2012 Jul;342(1):23-32.

MLR-1023 is a potent and selective allosteric activator of Lyn kinase in vitro - MLR-1023 is a potent and selective allosteric activator of Lyn kinase in vitro

Saporito MS, Ochman AR, Lipinski CA, Handler JA, Reaume AG. J Pharmacol Exp Ther. 2012 Jul;342(1):15-22.