MM-22

• Supplier: Tocris Bioscience
• Catalog: 0933
• Prices: $179.00, $745.00
• Sizes: 10 mg, 50 mg
• Cas Number: 956605-71-3
• Chemical Name: (3aS,4S,6aR)-Hexahydro-2-oxo-N-[2-[2-[2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]ethoxy]ethoxy]ethyl]-1H-thieno[3,4-d]imidazole-4-pentanamide
• Formula: C36H60N4O5S
• Molecular Weight: 660.95
• Purity: >98 %
• Description: Biotinylated anandamide analog; acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide. Blocks anandamide uptake (IC 50 = 0.5 μ M in HaCaT cells); prevents interaction with FAAH, CB 1 and TRPV1.

Product References

Characterization of biotin-anandamide, a novel tool for the visualization of - Characterization of biotin-anandamide, a novel tool for the visualization of

Fezza F, Oddi S, Di Tommaso M, De Simone C, Rapino C, Pasquariello N, Dainese E, Finazzi-Agro A, Maccarrone M. J Lipid Res. 2008 Jun;49(6):1216-23.

Evidence for the intracellular accumulation of anandamide in adiposomes. - Evidence for the intracellular accumulation of anandamide in adiposomes.

Oddi S, Fezza F, Pasquariello N, De Simone C, Rapino C, Dainese E, Finazzi-Agro A, Maccarrone M. Cell Mol Life Sci. 2008 Mar;65(5):840-50.

Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding - Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding

Oddi S, Fezza F, Pasquariello N, D'Agostino A, Catanzaro G, De Simone C, Rapino C, Finazzi-Agro A, Maccarrone M. Chem Biol. 2009 Jun 26;16(6):624-32.

Pitfalls and solutions in assaying anandamide transport in cells. - Pitfalls and solutions in assaying anandamide transport in cells.

Oddi S, Fezza F, Catanzaro G, De Simone C, Pucci M, Piomelli D, Finazzi-Agro A, Maccarrone M. J Lipid Res. 2010 Aug;51(8):2435-44.