MMK 1

• Supplier: Tocris Bioscience
• Catalog: 4511
• Prices: $129.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 271246-66-3
• Formula: C75H123N19O18S
• Molecular Weight: 1610.97
• Description: Potent and selective human formyl peptide receptor FPR2 agonist (EC 50 values are 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Induces migration of human monocytes and neutrophils via a chemotactic mechanism and enhances production of proinflammatory cytokines IL-1 β and IL-6. Also activates the neutrophil superoxide-generating NADPH-oxidase.

Product References

Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte - Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte

Hu JY, Le Y, Gong W, Dunlop NM, Gao JL, Murphy PM, Wang JM. J Leukoc Biol. 2001 Jul;70(1):155-61.

The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but - The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but

Karlsson J, Stenfeldt AL, Rabiet MJ, Bylund J, Forsman HF, Dahlgren C. Cell Calcium. 2009 May;45(5):431-8.