| Name | MMPIP hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3537 |
| Prices | $79.00, $169.00, $705.00 |
| Sizes | 1 mg, 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 479077-02-6 |
| Chemical Name | 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-onehydrochloride |
| Formula | C19H15N3O3.HCl |
| Molecular Weight | 369.8 |
| Purity | >98 % |
| Description | Potent allosteric mGlu 7 -selective receptor antagonist. Inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC 50 values are 26 and 610 nM). Displays intrinsic activity; increases forskolin-induced cAMP accumulation in the absence of an agonist (IC 50 = 15 nM), indicating inverse agonist activity. |
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